The impact of maternal age on the cost effectiveness of Down's syndrome screening.
نویسنده
چکیده
منابع مشابه
Screening for Down's syndrome: effects, safety, and cost effectiveness of first and second trimester strategies.
OBJECTIVE To compare the effects, safety, and cost effectiveness of antenatal screening strategies for Down's syndrome. DESIGN Analysis of incremental cost effectiveness. SETTING United Kingdom. MAIN OUTCOME MEASURES Number of liveborn babies with Down's syndrome, miscarriages due to chorionic villus sampling or amniocentesis, health care costs of screening programme, and additional costs...
متن کاملAntenatal maternal serum screening for Down's syndrome: results of a demonstration project.
OBJECTIVES To assess the implementation of antenatal screening for Down's syndrome in practice, using individual risk estimates based on maternal age and the three serum markers: alpha fetoprotein, unconjugated oestriol, and human chorionic gonadotrophin. DESIGN Demonstration project of Down's syndrome screening; women with a risk estimate at term of 1 in 250 or greater were classified as "sc...
متن کاملSecond trimester screening for Down's syndrome using maternal serum dimeric inhibin A.
OBJECTIVES To determine the second trimester Down's syndrome screening performance of maternal serum dimeric inhibin A, both alone and in combination with existing serum markers. SETTING A case-control set of serum samples from patients with Down's syndrome (52) and subjects with matched unaffected pregnancies obtained in a previous cohort study before second trimester amniocentesis and karyo...
متن کاملRetrospective audit of different antenatal screening policies for Down's syndrome in eight district general hospitals in one health region.
OBJECTIVE To compare the effectiveness of different screening policies for the antenatal detection of Down's syndrome. DESIGN Retrospective six year survey. SETTING Maternity units of eight districts. PARTICIPANTS Women who completed their pregnancies between 1 January 1994 and 31 December 1999 (155 501 deliveries). MAIN OUTCOME MEASURES Cases of Down's syndrome identified before 24 wee...
متن کاملRevised estimates of the maternal age specific live birth prevalence of Down's syndrome.
OBJECTIVES To revise the estimates of maternal age specific live birth prevalence of Down's syndrome in the absence of antenatal screening and selective termination using newly available data. SETTING AND DESIGN Data were used from the National Down Syndrome Cytogenetic Register (NDSCR), which contains information on nearly all antenatally or postnatally diagnosed cases of Down's syndrome in ...
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ورودعنوان ژورنال:
- British journal of obstetrics and gynaecology
دوره 103 6 شماره
صفحات -
تاریخ انتشار 1996